Clinical Trials - Wesley Research Institute
Wesley Research Institute

Clinical Trials Centre

The Clinical Trials Centre at Wesley Research Institute has been managing trials since 1994. Clinical trials are a type of research involving human volunteers dedicated to offering new and emerging treatment options to patients with various illnesses and diseases.

About the Clinical Trials Centre

The purpose of a clinical trial is to evaluate new approaches in treating medical conditions or diseases under controlled conditions. This involves determining how well people respond to new treatments, what side effects there are, how well they are tolerated or whether the new intervention is better than those that are already available.

The conduct of high-quality clinical trials is not only essential in the development of new medicines and medical devices, but they are also necessary to find new uses for existing medicines.

The Clinical Trials Centre enables patient participation in national and international phase I-IV clinical trials with a focus on evaluating new therapies, drugs, and diagnostic tools to drive discoveries into standard clinical practice. 

Engaged across four hospitals – The Wesley Hospital, St Andrew’s War Memorial Hospital, Buderim Private Hospital and St Stephen’s (Hervey Bay) – clinicians and patients located in both metropolitan and regional areas can participate.

Our patients are at the heart of all we do and that’s why Wesley Research Institute focuses on providing participants, researchers, and sponsors with a first-class, professional experience.  Our dedicated staff strive for a reputation of integrity and quality, delivering a warm, caring and inviting environment for all participants.

What clinical trials mean to participants

Clinical trials at Wesley Research Institute

A coeliac diet

Coeliac Research Study

Open for patient recruitment
A/Prof James Daveson and his team are developing a world leading multi-disciplinary research program for Coeliac Disease and Immune Health. However we can’t do this research without the coeliac community participating and volunteering to take part in clinical trials.
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Older lady sitting in wheelchair looking out the window

Motor Neurone Disease: Testing a potential new treatment for ALS

Open for patient recruitment
The research project is testing a potential new treatment for ALS or FTD called WVE-004, with the aim to decrease the neurogenerative symptoms in these patients.
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Immunoglobulin G4 (IgG4) Related Disease

Open for patient recruitment
The purpose of this study is to better understand the safety and side effects of Inebilizumab and to find out if it helps people with IgG4 related disease.
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A practitioner holding a persons leg and pressing their knee

Tranexamic Acid (TXA) Dosing in Primary Total Knee Arthroplasty

Open for patient recruitment
The purpose of the study is to evaluate a product called Tranexamic Acid (TXA) and its best use in patients who are undergoing total knee replacement.
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A person mixing baking ingredients in a bowl

Gluten Threshold Study

Open for patient recruitment
This study will compare small doses of gluten; Each participant is allocated either a dose of gluten or a placebo (which contains no gluten at all) through a process known as randomisation. The dose of gluten/placebo will be administered in a “gluten challenge”, which means that participants will ingest the gluten/placebo and then be observed for side effects.
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Lady doing a workout at home

Acumen For All

Open for patient recruitment
‘Enhancing treatment outcomes after gynaecological cancer’ (ACUMEN): Investigating the effect of exercise via telehealth on quality of life after treatment.
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Boy at dentist

Dental Enamel Defects Study

Closed for patient recruitment
Evaluating the prevalence of Coeliac Disease in children with Developmental Defects of Enamel.
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to support research


The Wesley Research Institute Clinical Trials Centre has extensive experience in both Investigator-initiated trials and Industry sponsored trials.

We tailor each clinical trial to the specific requirements of the sponsor or investigator. Below is a snapshot of some of our preferred service providers:

Radiology: UnitingCare Medical Imaging (i-Med)

Pathology: Sullivan Nicolaides Pathology

Pharmacy: Brands Pharmacy, The Wesley Hospital (Compounding Pharmacy)

Reach out to the Clinical Trial Centre team for an initial consultation with our team of trial experts.



Our site has highly experienced research staff with expertise across several therapeutic areas, research governance, quality, recruitment, sample collection/processing and more.


Wesley Research Institute is swipe card access only and is located on the 8th Floor of the East Wing of The Wesley Hospital.

It offers the following facilities for clinical trials:

  • Four clinical consultation rooms
  • Pathology Laboratory (including 2x vaccine refrigerators with back to base alarms and 24/7 temperature monitoring)
  • Dedicated drug safe
  • Two Patient Observation Lounges
  • Treatment Room
  • 3 x -80˚C freezers
  • -20˚C freezer
  • Refrigerated centrifuge
  • 3 x ambient centrifuges
  • Secure document storage
  • Ample monitoring space
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