TEVA Study - Wesley Research Institute
Wesley Research Institute

A Single-Dose Phase 1b, Randomized, Double-Blind, Placebo-Controlled Study to Characterise the Safety and Tolerability of TEV-53408 Administered Subcutaneously in Adults with Coeliac Disease 

Research Objectives





Total participants required


Study location

Wesley Research Institute

Study type

Industry Sponsored

Patient group

Coeliac Disease

About this clinical trial

The aim of this research study is to find out if a single injection of the research medicine, called TEV-53408, is safe and well-tolerated in adults with coeliac disease compared to a placebo injection.  

A placebo looks very similar to the research medicine but does not contain any active medicine. Researchers use a placebo to see if a research medicine works better or is safer than not taking anything at all. 



  • Be between 18 and 70 years old 
  • Have a diagnosis of coeliac disease with intestinal biopsy 
  • Have symptoms of coeliac disease when exposed to gluten 
  • Be on (or trying to be on) a gluten-free diet with no to moderate symptoms 
  • Have a positive HLA DQ2 or HLA DQ8 test 
  • Received of all regionally required vaccinations recommended for age and concurrent medical conditions and/or agrees to receive prior to participation in the study (if able) 

Lead investigator

  • Dr James Daveson

Experienced investigator

  • Dr Jennifer Schafer

Clinical trial coordinators

  • Chris Henderson
  • Leah Hingston

This clinical trial is now closed for recruitment

If you would like more information about this trial, please complete the contact form below.

You must be based in the Greater Brisbane region to be eligible for this study.
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