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This project aims to find new biomarkers for immunotherapy in patients with melanoma.

Research Objectives

Status

Current

Recruitment

Open

Patient Group

Cancer – Stage IV Melanoma

Study location

Wesley Research Insitute, The Wesley Hospital

Study type

Investigator Initiated

Finding new biomarkers for immunotherapy in patients with melanoma

Lead investigator

  • Private: Dr Agnieszka Malczewski

Clinical trial coordinator

  • Venita Bali

Technical title

Metabolomics in Enhancing Responses to Cancer ImmunoTherapy in Melanoma (MERIT-M)

About this research project

Cancer immunotherapy has been shown to provide patients with an excellent new type of treatment and is in common use world-wide. Unfortunately, we know that not all patients will respond to their immunotherapy treatment in the same way.

Responses to immunotherapy may be affected by a patient’s microbiome, or the community of bacteria that live in their bowel. This group of bacteria can influence the immune system by increasing or decreasing certain types of white cells, called T cells that are produced in the body. By analysing the bacteria, this project aims to find new biomarkers for immunotherapy in patients with melanoma.

 

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