Wesley Research Institute
Donate
Now

This project will develop new and highly precise predictive classifiers for early diagnosis and detection of Parkinson’s disease based on complex microbial signatures which will inform diagnosis, staging and classification of Parkinson’s disease patients in the clinic.

 

Research Objectives

Status

Current

Recruitment

Open

Study location

Wesley Research Institute, Wesley Research Institute, Queensland University of Technology

Study type

Investigator Initiated

Lead investigator

  • A/Prof John O’Sullivan

Experienced investigator

  • Dr Richard Gordon (QUT)

About this research project

It’s estimated that one in every 1,000 Australians have Parkinson’s disease with approximately 40 people diagnosed everyday. The number of people diagnosed with Parkinson’s disease has increased 17% in the last six years with costs to the community increasing by nearly 50%. It’s the second most common neurodegenerative disease after dementia in Australia.

There are currently no effective biomarkers to accurately diagnose Parkinson’s disease or predict disease progression. Pathological changes in the gut microbiota composition and metabolism occurs early in Parkinson’s disease which drives neuropathology and disease progression. Understanding and characterising the complex changes in gut microbiome composition will provide new opportunities for therapeutic targets and diagnostic biomarkers.

Interested in participating? Find out more information here.

Latest News

New Study Reveals Hidden Immune Activity in Cardiac Sarcoidosis Using Spatial Biology 

A new study led by researchers at Wesley Research Institute, published in the European Heart Journal—one of the world’s most widely read cardiology journals—marks a significant advance in cardiac sarcoidosis (CS) research.

New Research Program Transforming Cardiovascular Care

A new research program at Wesley Research Institute, led by Associate Professor Eliot Peyster, is bringing unique human tissue models, advanced spatial biology analyses, and implementation-focused computational and ‘AI’ tools into cardiovascular research.

Where Math Meets Medicine: Cooper’s Role in Transforming Cancer Care 

For Cooper, the future of cancer research lies at the intersection of numbers and biology. We caught up with Cooper, to learn how he’s diving into one of the most exciting and challenging areas of modern science: computational biology.
1 2 3 32
linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram