Wesley Research Institute
Donate
Now

This one year research project aims to compare two commonly used methods of draining the effusion to determine which one is best.

Research Objectives

Status

Current

Recruitment

Closed

Patient Group

Pleural Effusion

Study location

Wesley Research Institute

Study type

Investigator Initiated
find out if you’re eligible

Lead investigator

  • Dr Luke Garske

Clinical trial coordinators

  • Chris Henderson
  • Linda Pearce

Technical title

AMPLE-3: A Randomised Study Comparing Combined Indwelling Pleural Catheter (IPC) and Talc Pleurodesis with Video-Assisted Thoracoscopic Surgery (VATS) for the Management of Patients with Malignant Pleural Effusion

About this research project

The lung is covered by a thin lining which produces a very small amount of fluid to lubricate the lungs during breathing. Cancers can spread to this lining causing a build-up of fluid. This is called a malignant pleural effusion. The increased fluid can compress the lungs causing breathlessness. Draining the fluid can ease symptoms but it usually rapidly re-accumulates and needs further drainages.

This one year research project aims to compare two commonly used methods of draining the effusion to determine which one is best. One method involves a surgical procedure (VATS) and the other involves insertion of a long-term flexible chest tube (IPC). IPC and surgical pleurodesis are known to be safe procedures and are both commonly used; however, no one knows if one is better than the other at preventing the fluid from returning and further procedures being required.

 

Latest News

Queensland claims world-first Chair in Spatial Medicine  

In a landmark move in diagnosing and treating chronic disease, Queensland has unveiled the world’s first Chair in Spatial Medicine – a prestigious, philanthropically-funded research leadership position appointed to Associate Professor Arutha Kulasinghe. 

Gluten Threshold Study Findings

WRI researchers have made a groundbreaking discovery showing that even extremely small amounts of gluten can trigger measurable immune activation in people with treated coeliac disease – findings that could help refine international food labelling standards.  

How Kira is Helping to Shape Global Coeliac Research

When Kira was invited to participate in the Gluten Threshold Study, led by Coeliac Disease & Immune Health Research Program Clinical Director Dr James Daveson, Kira didn’t hesitate. The study’s findings are expected to influence international food labelling standards – an outcome that gives Kira a genuine sense of purpose. 
1 2 3 34
linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram