Dr Eliot Peyster

Dr Eliot Peyster is the Director of Cardiovascular Translational Medicine at the Wesley Research Institute and an Adjunct Professor of Medicine at the University of Pennsylvania and the University of Queensland. He is a cardiologist and transplant physician whose research integrates spatial biology, advanced computational methods, and novel human tissue models to drive precision medicine breakthroughs in cardiovascular disease, heart failure, and organ transplantation. 

Dr Peyster has led pioneering studies applying machine learning and computer vision to improve diagnosis and prediction in diseases of both the native and transplanted hearts, earning national research awards, multiple patents, and international recognition. Building on this expertise, his group is now establishing real-world workflows for AI and computer-vision-based clinical decision support.  In pursuit of further real-world impact, his group is now developing living human heart tissue platforms for ex-vivo therapeutic trials — enabling direct testing of new drugs and interventions in real human myocardium before they reach patients. 

Current research focuses on uncovering human-specific mechanisms and biomarkers in cardiac sarcoidosis, coronary artery disease, transplant rejection, and heart failure, while developing new translational pipelines that accelerate therapies from the lab to the clinic.