Allie Lam
About
Dr Allie Lam is a Research Assistant at the Queensland Spatial Biology Centre (QSBC) with expertise in immunology and cancer immunotherapy. She completed a Bachelor of Science (Honours) at the University of Melbourne, specialising in immunology and microbiology, and a PhD in Biomedical Sciences at The University of Queensland, where her research focused on immune modulation for cancer immunotherapy.
At the QSBC, Dr Lam supports collaborative projects using advanced spatial and tissue-based profiling approaches to characterise cellular heterogeneity and biomarker expression in complex tissues. Her work aligns with the centre’s mission to enable high-quality spatial biology research and to support translational outcomes across cancer and other disease areas.
Dr Lam has held research roles at the Frazer Institute, Faculty of Medicine, The University of Queensland, contributing to discovery and translational research programs spanning spatial transcriptomics, natural killer (NK) cell biology, cell-based immunotherapies, and tumour–immune interactions. She brings experience working across multidisciplinary teams to support complex research projects from experimental design through to data generation and analysis.
Qualifications
Doctor of Philosophy in Immunology, The University of Queensland
Bachelor of Science with Class I Honours, University of Melbourne
Featured Publications
Wong J.K.M.*, Lam P.Y.*, Coleborn E.*, et al., Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapy. Molecular Therapy. (* co-first author). https://doi.org/10.1016/j.ymthe.2025.11.021
Lam P.Y.*, Omer N.*, Wong J.K.M.*, et al., Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR. Clinical Translational Medicine, 15:e70140. (* co-first author). https://doi.org/10.1002/ctm2.70140
Vo T., Prakrithi P., Jones K., Yoon S., Lam P.Y., et al., 2025. Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues. The Journal of Pathology, 265(3), 274–288. https://doi.org/10.1002/path.6383
Pham, D., Tan, X., Balderson, B., Xu, J., Grice, L.F., Yoon, S., Willis, E.F., Tran, M., Lam, P.Y., et al., 2023. Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues. Nature Communications, 14 (1) 7739 1-25. https://doi.org/10.1038/s41467-023-43120-6
Raghubar, A.M., Pham, D.T., Tan, X., Grice, L.F., Crawford, J., Lam, P.Y., et al., 2022. Spatially resolved transcriptomes of mammalian kidneys illustrate the molecular complexity and interactions of functional nephron segments. Frontiers in Medicine, 9 873923 873923. https://doi.org/10.3389/fmed.2022.873923
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