Wesley Research Institute
Donate
Now

This one year research project aims to compare two commonly used methods of draining the effusion to determine which one is best.

Research Objectives

Status

Current

Recruitment

Closed

Patient Group

Pleural Effusion

Study location

Wesley Research Institute

Study type

Investigator Initiated
find out if you’re eligible

Lead investigator

  • Dr Luke Garske

Clinical trial coordinators

  • Chris Henderson
  • Linda Pearce

Technical title

AMPLE-3: A Randomised Study Comparing Combined Indwelling Pleural Catheter (IPC) and Talc Pleurodesis with Video-Assisted Thoracoscopic Surgery (VATS) for the Management of Patients with Malignant Pleural Effusion

About this research project

The lung is covered by a thin lining which produces a very small amount of fluid to lubricate the lungs during breathing. Cancers can spread to this lining causing a build-up of fluid. This is called a malignant pleural effusion. The increased fluid can compress the lungs causing breathlessness. Draining the fluid can ease symptoms but it usually rapidly re-accumulates and needs further drainages.

This one year research project aims to compare two commonly used methods of draining the effusion to determine which one is best. One method involves a surgical procedure (VATS) and the other involves insertion of a long-term flexible chest tube (IPC). IPC and surgical pleurodesis are known to be safe procedures and are both commonly used; however, no one knows if one is better than the other at preventing the fluid from returning and further procedures being required.

 

Latest News

Thank you to all who joined our Advocates Event – Spatial Biology: A New Frontier of Precision Medicine

On 24 Nov, the Wesley Hospital Auditorium saw a community of medical research advocates come together to learn more about spatial biology and the latest research efforts from the Wesley Research Institute's Queensland Spatial Biology Centre.

The Impact of Financial Stress of a Gluten-Free Diet for People with Coeliac Disease: New Research in Australia 

WRI researchers are calling upon people living with coeliac disease in Australia to participate in research to map the quality of life in this current cost-of-living crisis and whether this is impacting their ability to adhere to a gluten-free diet.

Give Hope a Name This Christmas

Your support can play a vital role in advancing life-changing research at Wesley Research Institute. Our scientists are uncovering new ways to personalise treatment and improve outcomes for people facing serious illnesses, like cancer. 
1 2 3 30
linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram