The challenge for many surgeons and oncologists is understanding if the cancer is confined to the prostate or has spread to the lymph nodes, one of the early and most likely sites.
In 2014, approximately 52% of Australian men undergoing a radical prostatectomy for prostate cancer also underwent a pelvic lymph node
However, final analysis of these dissections found that only a small fraction of these men actually have cancer in their lymph nodes.
Understanding if these nodes are cancerous prior to surgery would reduce the unnecessary removal of lymph nodes.
The MAGNIFI Trial led by interventional radiologist, Dr Nick Brown, is focused on a novel imaging technique to provide a reliable staging assessment of pelvic lymph nodes in prostate cancer.
In the vast majority of men, we expect these imaging tests to identify no cancer, allowing surgeons to confidently avoid having to perform a pelvic node dissection.
If this trial is successful, this imaging method could be applicable to any disease in which cancer spreads to lymph nodes, such as colon cancer, bowel cancer, cervical cancer, melanoma, penile cancer, head and neck cancers.
This project has been made possible through the generous philanthropic support of The Thorsen Foundation, Vidyajey Foundation, The Albrecht Foundation and many others.
Presentations & Events
Prostate Cancer Research: Targeting Improvements in Men's Health
Interventional Radiologist Dr Nick Brown is actively involved in critical research into oncological imaging, particularly urological imaging and in August 2019, he presented at Wesley Medical Research on his research into innovative imaging techniques that could provide more accurate detection of cancer in lymph nodes.