Tranexamic Acid (TXA) Dosing in Primary Total Knee Arthroplasty - Wesley Research Institute
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The purpose of the study is to evaluate a product called Tranexamic Acid (TXA) and its best use in patients who are undergoing total knee replacement.

Research Objectives

Status

Current

Estimated completion

December 2023

Total participants required

80

Study location

The Wesley Hospital

Study Type

Investigator Initiated

About this clinical trial

The purpose of the study is to evaluate a product called Tranexamic Acid (TXA) and its best use in patients who are undergoing total knee replacement. The product is currently used to reduce bleeding during and after surgical procedures. This can lessen the chance of you needing a blood transfusion and may decrease pain, swelling and recovery time following the operation. Tranexamic Acid is already routinely used by surgeons for patients having joint replacements but there is currently no accurate information about the best dosing of the drug to achieve optimal patient outcomes. This study will assess whether different treatment durations will lead to better results for patients.

Eligibility

Do you meet the following criteria?

People undergoing primary unilateral Total Knee Arthroplasty.

Additional information

You can find out more about this clinical trial by visiting the ANZCTR website.

Lead investigators

  • Dr Sue Clark

Technical title

A Prospective, Randomised Non-Blinded Pilot Study to Optimise Oral Tranexamic Acid Dosing in Primary Total Knee Arthroplasty (TXA002)

Register your interest

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