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This study aims to evaluate, ADAM 2.0, a new medical device that works as a form of male contraception. 

Research Objectives

Status

Current

Recruitment

Closed

Total participants required

10

Study location

Wesley Research Institute, St Andrew's War Memorial Hospital

Study type

Industry Sponsored

Patient group

Adult males who are fertile and suitable for a vasectomy

About this clinical trial

This first in-human study aims to evaluate ADAM™ 2.0, a new male contraceptive device implanted into the vas deferens (tubes which sperms travel through) by a doctor. Unlike a vasectomy, which is usually permanent and requires complex surgery to reverse, ADAM™ 2.0 may allow sperm flow to return naturally over time. Made from safe, non-toxic materials used in other surgeries, ADAM™ 2.0 is expected to be low risk, similar to a vasectomy. This study will recruit 30 participants across 3 study sites within Australia. All participants will also be followed for up to two years to monitor sperm levels and implant dissolution by the body, with an offer of a vasectomy at no-cost (if applicable). ADAM™ 2.0 does not protect against STIs and is not yet proven to prevent pregnancy, so other birth control methods must be used during the study.  

Trial Registration information – https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=388668 

Eligibility

  • Male adults aged 25 to 55 years of age (inclusive)
  • Possess a healthy sperm count and motility based on semen tests conducted. 
  • Seek to undergo a vasectomy as a long-term form of contraception
  • Must use alternative forms of contraception with any female partner during the study duration 

Lead investigator

  • Professor Eric Chung

Clinical trial coordinator

  • Chris Henderson

Technical title

Open-label, Multi-Centre, First-in-Human Study to Assess the Safety, Efficacy and Feasibility of Implanting ADAM™ 2.0 in Fertile Males Who Are Suitable for a Vasectomy

This clinical trial is closed for recruitment

If you would like more information about this clinical trial, please complete the contact form below.

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